Thursday, March 17, 2011

ScienceDaily Health Headlines -- for Thursday, March 17, 2011

ScienceDaily Health Headlines

for Thursday, March 17, 2011

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Omalizumab relieves seasonal asthma attacks in youth, study finds (March 17, 2011) -- A drug that targets the antibody immunoglobulin E, a key player in asthma, nearly eliminated seasonal increases in asthma attacks and decreased asthma symptoms among young people living in inner city environments, a clinical trial has found. ... > full story

Improving the infant gut ‘microbiome’ (March 17, 2011) -- While next-generation sequencing-based research of gut microbiomes will ultimately benefit all members of the population, to date there has been a particular emphasis on investigating and, where necessary, altering the microbiota present in the gut of the elderly, infants and obese individuals. For example, evidence exists that early colonization of the infant gastrointestinal tract by microbes is crucial for the overall health of the infant. ... > full story

'Pre-baby blues' due to lack of support from partner, study finds (March 17, 2011) -- Pregnancy is meant to be a joyous time however some women experience overwhelming "baby blues" before the birth of their child. Anxiety and depression during pregnancy can result in premature birth, or low birth weight, and impact the child's health even into early school years. New research shows that a bad relationship with their husband or partner is the strongest predictor of maternal emotional distress. ... > full story

Some blind people 'see' with their ears, neuropsychologists show (March 17, 2011) -- Neuropsychologists compared the brain activity of people who can see and people who were born blind, discovering that the part of the brain that normally works with our eyes to process vision and space perception can actually rewire itself to process sound information instead. ... > full story

New therapy found for rare lung disorder (March 17, 2011) -- Researchers have found that the FDA-approved drug sirolimus, used primarily to prevent rejection in organ transplant patients, stabilized lung function in women with lymphangioleiomyomatosis. ... > full story

Altered gene protects some African-Americans from coronary artery disease (March 17, 2011) -- Scientists have discovered that a single alteration in the genetic code of about a fourth of African-Americans helps protect them from coronary artery disease, the leading cause of death in Americans of all races. ... > full story

Current U.S. juvenile treatment methods for violent offenders costly, ineffective, researcher finds (March 17, 2011) -- Multisystemic therapy is more effective in the lives of troubled youth and costs less than the current US juvenile treatment methods, experts say. ... > full story

Neuro signals study gives new insight into brain disorders (March 16, 2011) -- Research into how the brain transmits messages to other parts of the body could improve understanding of disorders such as epilepsy, dementia, multiple sclerosis and stroke. Scientists have identified a protein crucial for maintaining the health and function of the segment of nerve fibers that controls transmission of messages within the brain. ... > full story

More insight into Sensenbrenner syndrome (March 16, 2011) -- Dutch researchers have found a new gene for Sensenbrenner syndrome. The mutation adds support to the hypothesis that defects in ciliar transport are the cause of the disease. ... > full story

Zooming in on the weapons of Salmonella (March 16, 2011) -- Bacteria like salmonellae infect their host cells by needle-shaped extensions which they create in large numbers during an attack. Scientists have now employed recently developed methods of cryo-electron microscopy and have been able to clarify the structure of this infection apparatus on the near-atomic scale. The exact knowledge of the needles' building plan may help to develop substances that interfere with its function and thus prevent infection. ... > full story

'Ivory wave' may be new legal high after 'miaow miaow' (mephedrone) ban (March 16, 2011) -- A new legal high has emerged that seems to be replacing the banned substance mephedrone or "miaow miaow," warns a critical care paramedic in a new article. ... > full story

Pig model of cystic fibrosis improves understanding of disease (March 16, 2011) -- Using a newly created pig model that genetically replicates the most common form of cystic fibrosis, researchers have now shown that the CF protein is "misprocessed" in the pigs and does not end up in the correct cellular location. This glitch leads to disease symptoms, including gastrointestinal abnormalities and lung disease in the pigs, which mimic CF in humans. ... > full story

How common immune booster works: Research may lead to new and improved vaccines (March 16, 2011) -- Alum is an adjuvant (immune booster) used in many common vaccines, and researchers have now discovered how it works. ... > full story

Why some microbial genes are more promiscuous than others (March 16, 2011) -- While most organisms get their genes from their parents, bacteria also regularly pick up genes from more distant relatives. This ability to "steal" snippets of DNA from other species is responsible for the rapid spread of drug resistance among disease-causing bacteria. A new study of more than three dozen species - including the microbes responsible for pneumonia, ulcers and plague -- settles a longstanding debate about why bacteria are more likely to steal some genes than others. Bacteria are more likely to adopt 'loner' genes than genes that are well-connected, the study finds. ... > full story

Improving risk/benefit estimates in new drug trials (March 16, 2011) -- It's all too familiar: researchers announce the discovery of a new drug that eradicates disease in animals. Then, a few years later, the drug bombs in human trials. Now, two medical ethicists argue that this pattern of boom and bust may be related to the way researchers predict outcomes of their work in early stages of drug development. ... > full story

New 'dissolvable tobacco' products may increase risk of mouth disease (March 16, 2011) -- The first study to analyze the complex ingredients in the new genre of dissolvable tobacco products has concluded that these pop-into-the-mouth replacements for cigarettes in places where smoking is banned have the potential to cause mouth diseases and other problems. ... > full story

New way to test cancer drugs (March 16, 2011) -- A scientist's nanopolymer would make it easier and cheaper for drug developers to test the effectiveness of a widely used class of cancer inhibitors. He created the 'pIMAGO nanopolymer' that can be used to determine whether cancer drugs have been effective against biochemical processes that can lead to cancer cell formation. ... > full story

Brain injuries rise sharply in minor hockey after bodychecking rules relaxed, Canadian study shows (March 16, 2011) -- Minor league hockey players in the Atom division are more than 10 times likely to suffer a brain injury since bodychecking was first allowed among the 9- and 10-year-olds. ... > full story

Parental monitoring of opposite-gender child may decrease problem drinking in young adults (March 16, 2011) -- Young adults whose parents monitor their social interactions may be less likely to display impulsive behavior traits and to have alcohol-related problems, a new study suggests. The level of monitoring is linked to parenting style, and the link is stronger with the parent of the opposite gender. ... > full story

Laser beam makes cells 'breathe in' water and potentially anti-cancer drugs (March 16, 2011) -- Shining a laser light on cells and then clicking off the light-makes the cells "breathe in" surrounding water, providing a potentially powerful delivery system for chemotherapy drugs, as well as a non-invasive way to target anti-Alzheimer's medicines to the brain. ... > full story

Does selenium prevent cancer? It may depend on which form people take (March 16, 2011) -- Scientists are reporting that the controversy surrounding whether selenium can fight cancer in humans might come down to which form of the essential micronutrient people take. It turns out that not all "seleniums" are the same -- the researchers found that one type of selenium supplement may produce a possible cancer-preventing substance more efficiently than another form of selenium in human cancer cells. ... > full story

Integrity of the brain's reward system is linked to relapse following treatment (March 16, 2011) -- The brain reward system (BRS) is involved in developing/maintaining addictive disorders, as well as relapse. New findings show that alcohol dependent individuals -- both future abstainers and relapsers -- have significantly thinner cortices in the BRS and throughout the entire brain. Findings support the influence of neurobiological factors on relapse. ... > full story

Insulin-releasing switch discovered (March 16, 2011) -- Researchers believe they have uncovered the molecular switch for the secretion of insulin -- the hormone that regulates blood sugar -- providing for the first time an explanation of this process. In a new study, the researchers say the work solves a longtime mystery and may lead to better treatments for type 2 diabetes, the most common form of the disease. ... > full story

Inflammation behind heart valve disease, research suggests (March 16, 2011) -- Researchers in Sweden have shown that a specific inflammatory factor may be important in the development of the heart valve disease aortic stenosis. The results suggest that anti-inflammatory medication could be a possible new treatment. ... > full story

An early age at first drink combined with stressful life events can lead to heavy drinking (March 16, 2011) -- Researchers believe that an early age at first drink (AFD) may lead to greater stress-induced drinking. A new study examines interactions between AFD and stressful life events on drinking during young adulthood. Findings indicate a strong link between an early AFD and later heavy drinking when confronted by a high load of stressful life events. ... > full story

New device holds promise of making blood glucose testing easier for patients with diabetes (March 16, 2011) -- Bioengineers and physicians are developing a device designed to make it easier for people with diabetes to monitor their health. Current monitoring devices require that people prick themselves to draw blood for a glucose-level test sample -- often several times a day. The new device would enable accurate glucose-level testing by using tear fluid as a test sample -- relieving people from having to draw blood repeatedly. ... > full story

A good sense of smell is more a product of training than good genes (March 16, 2011) -- Do you need to be an expert to have a good nose? It turns out the answer is yes! Having a good nose is not something we are born with, but instead just a matter of training, new research suggests. ... > full story

Proteins may affect behavior and physiology of female mosquitoes (March 16, 2011) -- Researchers have identified 93 seminal fluid proteins and 52 sperm male-derived proteins that include candidates likely to affect the behavior and physiology of female mosquitoes of the species, Aedes aegypti. ... > full story

The development of better biotech enzymes (March 16, 2011) -- Enzymes are proteins that speed up chemical reactions, such as laundry detergent digesting protein stains, which are otherwise very difficult to remove. Scientists have now demonstrated a fundamental principle in changing the activity of enzymes by means of protein engineering. ... > full story

Prevalence of heavy smokers in US decreases (March 16, 2011) -- From 1965 to 2007, the population prevalence of persons who smoked 20 or more cigarettes per day declined significantly, and there was also a decrease in the prevalence of smoking 10 or more cigarettes a day, with these declines greater in California than in the rest of the US, according to a new study. ... > full story

Malaria drug slows pancreatic cancer growth in mouse models (March 16, 2011) -- Scientists report they have used hydroxychloroquine, a drug routinely prescribed for malaria and rheumatoid arthritis, to shrink or slow the growth of notoriously resistant pancreatic tumors in mice. ... > full story

Unprecedented view of protein folding may help develop brain disease therapies (March 16, 2011) -- When vital proteins in our bodies are misfolded, debilitating diseases can result. If researchers could see the folding happen, they might be able to design treatments for some of these diseases. But many of our most critical proteins are folded, hidden from sight, inside tiny molecular chambers. Now researchers have gotten the first-ever peek inside one of these protein-folding chambers as the folding happened, and the folding mechanism they saw surprised them. ... > full story

Treatments for recurring TB infection failing the developing world, study finds (March 16, 2011) -- The standard approach to re-treating tuberculosis (TB) in low and middle income settings is failing, according to new research. Researchers call for improved access to rapid diagnostics for drug resistant TB, second-line TB treatment and antiretroviral HIV therapy. ... > full story

New study predicts cholera epidemic in Haiti will far exceed UN projections (March 16, 2011) -- A new study predicts that the cholera epidemic in Haiti this year will be far worse than United Nations' projections, which had estimated 400,000 cases of the diarrheal disease over the course of the epidemic. ... > full story

New microscope decodes complex eye circuitry (March 16, 2011) -- The properties of optical stimuli need to be conveyed from the eye to the brain. To do this efficiently, the relevant information is extracted by pre-processing in the eye. Using a novel microscopy method researchers have now discovered that the distribution of the synapses between ganglion cells and interneurons follows highly specific rules. ... > full story

New vaccine candidate shows strong potential to prevent highly contagious norovirus (March 16, 2011) -- Scientists have found that an experimental vaccine against human norovirus -- the bug behind 90 percent of highly contagious nonbacterial illnesses causing diarrhea and vomiting -- generates a strong immune response in mice without causing the animals any harm. Using a novel viral vector-based method to grow and deliver the vaccine that has shown promise in other agents designed to fight such infections as HIV and hepatitis C, they are the first to test this vaccine design method's effectiveness against the human norovirus. ... > full story

Vitamin D deficiency in cirrhosis (March 16, 2011) -- A research team from Denmark examined the vitamin D status in patients with alcoholic cirrhosis compared to those with primary biliary cirrhosis. They found that vitamin D deficiency in cirrhosis relates to liver dysfunction rather than etiology, with lower levels of vitamin D in alcoholic cirrhosis than in primary biliary cirrhosis. ... > full story

Association found between industry funding and promotional pieces on menopausal hormone therapy (March 16, 2011) -- There may be a link between receiving industry funding for speaking, consulting, or research, and the publication of apparently promotional opinion pieces on menopausal hormone therapy. Furthermore, such publications may encourage physicians to continue prescribing these therapies to women of menopausal age. ... > full story

Optical illusions show vision in a new light (March 15, 2011) -- Optical illusions have fascinated humans throughout history. Greek builders used an optical illusion to ensure that that their columns appeared straight (they built them with a bulge) and we are all intrigued by the mental flip involved in the case of the young girl/old woman faces. New research demonstrates a more serious use of these illusions in understanding how the brain assesses relative size. ... > full story

Why some people are apple-shaped and others are pear-shaped (March 15, 2011) -- Scientists have shed light on why some people are apple-shaped and others are pear-shaped. Researchers have pinpointed a protein that plays a part in how fat is stored in the body. ... > full story

Finding of long-sought drug target structure may expedite drug discovery (March 15, 2011) -- Researchers have solved the 3-D structure of a key biological receptor. The finding has the potential to speed drug discovery in many areas, from arthritis to respiratory disorders to wound healing, because it enables chemists to better examine and design molecules for use in experimental drugs. ... > full story

How tuberculosis bacteria manage to survive inside body’s macrophage cells (March 15, 2011) -- Tuberculosis kills two million people each year. Researchers in Sweden are now presenting new findings that show how the bacterium that causes the disease manages to survive inside the body’s macrophage cells in order eventually to blow them up and spread their infection. ... > full story

The new adulthood: Extended parental support as a safety net (March 15, 2011) -- A new study shows that contrary to popular anxieties about slacker young adults who refuse to grow up, or indulgent parents who stifle their adult children's development by continuing to support them, there is evidence that parental assistance in early adulthood promotes progress toward autonomy and self-reliance. ... > full story

Bilinguals see the world in a different way, study suggests (March 15, 2011) -- Scientists have found that regularly speaking in a second language makes you literally see the world in a different way. Color perception is an ideal way of testing bilingual concepts because there is a huge variation between where different languages place boundaries on the color spectrum. ... > full story

Lung cancer metastasis: Researchers find key component -- and possible way to block it (March 15, 2011) -- Researchers have discovered a new, key component in the spread of lung cancer as well as a likely way to block it with drugs now in clinical trial. ... > full story

Potentially pathogenic microbes growing on at least half of all orthodontic retainers, study suggests (March 15, 2011) -- Insufficient cleaning could allow build-up of microbes on orthodontic retainers, researchers have found. Researchers looked at the types of microbes which live on retainers. This study found potentially pathogenic microbes growing on at least 50% of the retainers. ... > full story

Why argue? Helping students see the point (March 15, 2011) -- Read the comments on any website and you may despair at Americans' inability to argue well. Thankfully, educators now name argumentative reasoning as one of the basics students should leave school with. ... > full story

Surgical technique helps adult male survivors of childhood cancer regain fertility (March 15, 2011) -- A new study has shown that a surgical technique called microdissection testicular sperm extraction can effectively locate and extract viable sperm in more than one-third of adult male childhood cancer survivors who were previously considered sterile due to prior chemotherapy treatment. ... > full story


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