Friday, April 15, 2011

ScienceDaily Health Headlines -- for Friday, April 15, 2011

ScienceDaily Health Headlines

for Friday, April 15, 2011

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Enzyme crucial to DNA replication may provide potent anti-cancer drug target (April 15, 2011) -- An enzyme essential for DNA replication and repair in humans works in a way that might be exploited as anti-cancer therapy, say researchers. ... > full story

Sensor determines if packaged meat has spoiled (April 15, 2011) -- When it comes to packaged fish or meat, it is nearly impossible to distinguish between fresh goods and their inedible counterparts. Researchers have now developed a sensor film that can be integrated into the package itself, where it takes over the role of quality control. And if the food has spoiled, it changes color to announce the fact. ... > full story

Human factors/ergonomics research leads to improved bunk bed safety standards (April 15, 2011) -- Ryan was just four years old when he went to sleep on his bunk bed one night and never woke up. His mother found him strangled to death the next morning with his neck caught between the vertical post of his side ladder and mattress. ... > full story

Study links inflammation in brain to some memory decline (April 15, 2011) -- High levels of a protein associated with chronic, low-grade inflammation in the brain correlate with aspects of memory decline in otherwise cognitively normal older adults, according to a new study. ... > full story

Changes in 'good' fatty acid concentration of inner organs might be largely independent of diet (April 15, 2011) -- We are all encouraged to eat polyunsaturated fatty acids, as these are "good for us". The (relative) levels of particular classes of polyunsaturated fatty acids have been associated with a plethora of human illnesses. New research suggests that changes in fatty acid concentration of inner organs might be largely independent from diet composition. ... > full story

Aggressive glycemic control in diabetic CABG patients does not improve survival, study suggests (April 15, 2011) -- Surgeons have found that in diabetic patients undergoing coronary artery bypass graft surgery, aggressive glycemic control does not result in any significant improvement of clinical outcomes as compared with moderate control. The findings also found the incidence of hypoglycemic events increased with aggressive glycemic control. ... > full story

People who overuse credit believe products have unrealistic properties (April 15, 2011) -- Researchers say people who overuse credit have very different beliefs about products than people who spend within their means. Following a new study, researchers said that many people buy products thinking that the items will make them happier and transform their lives. ... > full story

Treating high blood pressure, cholesterol, diabetes may lower risk of Alzheimer's disease (April 14, 2011) -- Treating high blood pressure, high cholesterol, diabetes and other vascular risk factors may help lower the risk of Alzheimer's disease in people who already show signs of declining thinking skills or memory problems. ... > full story

New clues about how to prevent aortic aneurysm in patients with Marfan syndrome (April 14, 2011) -- Scientists whose laboratory studies first suggested that an FDA-approved drug, losartan, might prevent the potentially deadly enlargement of the aorta caused by Marfan syndrome now have an even clearer picture of the cellular signals that contribute to the disease. While a clinical trial testing losartan's ability to slow progression of aneurysm in people with Marfan syndrome continues, ongoing research is generating data that will help guide treatment decisions and inform efforts to develop alternate therapies. ... > full story

Wikipedia deemed a reliable source for political information, according to study (April 14, 2011) -- Not so long ago Wikipedia was considered a playground for Capitol Hill staffers to game the system and make "the boss look better and the opponent look ridiculous." Now a new study of articles related to candidates for governor across the US found very few inaccuracies. ... > full story

Weak evidence for word-order universals: Language not as 'innate' as thought? (April 14, 2011) -- About 6,000 languages are spoken today worldwide. How this wealth of expression developed, however, largely remains a mystery. A group of researchers in the Netherlands has now found that word-orders in languages from different language families evolve differently. This contradicts the common understanding that word-order develops in accordance with a set of universal rules, applicable to all languages. Researchers have concluded that languages do not primarily follow innate rules of language processing in the brain. Rather, sentence structure is determined by the historical context in which a language develops. ... > full story

Predicting Alzheimer's: Thinning of key cortical areas predicts dementia up to a decade in advance (April 14, 2011) -- Subtle differences in brain anatomy among older individuals with normal cognitive skills may be able to predict both the risk of developing Alzheimer's disease in the following decade and how quickly symptoms of dementia would develop. ... > full story

Lung perfusion system allows high-risk lungs to be safely transplanted, study suggests (April 14, 2011) -- For the first time, scientists have shown in a clinical trial that the Toronto XVIVO System can safely and effectively treat, re-assess and improve the function of high-risk donor lungs so that they can be successfully transplanted into patients. The use of this technique could significantly expand the donor organ pool and improve outcomes after transplantation. ... > full story

Too much information? Risk-benefit data does not always lead to informed decision-making (April 14, 2011) -- Giving patients data about the risks and benefits of a medical intervention is not always helpful and may even lead them to irrational decisions, according to a new article. That finding calls into question whether it is essential to disclose quantitative data to patients to help them make informed decisions. An accompanying commentary calls for experimental evidence to determine the best way to provide information to patients. ... > full story

Possible cause of salt-induced hypertension identified (April 14, 2011) -- New research shows that salt intake raises blood pressure because it makes it harder for the cardiovascular system to simultaneously juggle the regulation of blood pressure and body temperature. ... > full story

Polluted air leads to disease by promoting widespread inflammation (April 14, 2011) -- Chronic inhalation of polluted air appears to activate a protein that triggers the release of white blood cells, setting off events that lead to widespread inflammation, according to new research in an animal model. This finding narrows the gap in researchers' understanding of how prolonged exposure to pollution can increase the risk for cardiovascular problems and other diseases. ... > full story

Challenges in stemming the spread of resistant bacteria in intensive care (April 14, 2011) -- Expanded use of active surveillance for bacteria and of barrier precautions -- specifically, gloves and gowns -- did not reduce the transmission of two important antibiotic-resistant bacteria in hospital-based settings, according to a clinical trial conducted in 18 intensive care units in the United States. Incomplete compliance by health care providers with recommended hand hygiene procedures and the use of gloves and gowns, along with time lags in confirming the presence of bacteria in patients, may have contributed to the findings. ... > full story

Most substance–dependent individuals report poor oral health (April 14, 2011) -- Researchers have found that the majority of individuals with substance dependence problems report having poor oral health. They also found that opioid users, in particular, showed a decline in oral health over the period of one year. ... > full story

Anti-aging hormone Klotho inhibits renal fibrosis, cancer growth (April 14, 2011) -- A natural hormone known to inhibit aging can also protect kidneys against renal fibrosis researchers have demonstrated. ... > full story

Drug potency: What happens in space? (April 14, 2011) -- Some of the pharmaceuticals intended for the treatment of minor illnesses of astronauts in space may require special packaging and reformulation to remain stable for long periods in the space environment. That's according to a new study that suggests that some of the pharmaceuticals stored on space flights may have shorter shelf-life than they do on Earth. ... > full story

Are your values right or left? The answer is more literal than you think (April 14, 2011) -- Up equals good, happy, optimistic; down the opposite. Right is honest and trustworthy. Left, not so much. That's what language and culture tell us. "We use mental metaphors to structure our thinking about abstract things," says a psychologist, "One of those metaphors is space." ... > full story

Brain nerve stimulation could speed up learning, study suggests (April 14, 2011) -- In a breakthrough that may aid treatment of learning impairments, strokes, tinnitus and chronic pain, researchers have found that brain nerve stimulation accelerates learning in laboratory tests. Another major finding of the study involves the positive changes detected after stimulation and learning were complete. Researchers monitoring brain activity in rats found that brain responses eventually returned to their pre-stimulation state, but the animals could still perform the learned task. ... > full story

New drug may reduce seizures in epilepsy (April 14, 2011) -- A new drug called perampanel appears to significantly reduce seizures in people with hard-to-control epilepsy, according to results of the first clinical trial to test the higher 12 mg dose of the drug. ... > full story

Injectable gel could spell relief for arthritis sufferers (April 14, 2011) -- Some 25 million people in the United States alone suffer from rheumatoid arthritis or its cousin osteoarthritis, diseases characterized by often debilitating pain in the joints. Now researchers report an injectable gel that could spell the future for treating these diseases and others. ... > full story

Needle-free test for premature babies (April 14, 2011) -- Scientists have pioneered a new needle-free test to take the sting out of medicine testing in premature babies. The research will not only lead to greater accuracy in prescribing, but will also significantly reduce the trauma of such tests for newborn infants and their families. ... > full story

Your flaws are my pain: Experience of vicarious embarrassment is linked to empathy (April 14, 2011) -- Today, there is increasing exposure of individuals to a public audience. Television shows and the Internet provide platforms for this and, at times, allow observing others' flaws and norm transgressions. Regardless of whether the person observed realizes their flaw or not, observers in the audience experience vicarious embarrassment. For the first time, such vicarious embarrassment experiences as well as their neural basis have been investigated. ... > full story

Experimental Alzheimer's disease drugs might help patients with nerve injuries (April 14, 2011) -- Drugs already in development to treat Alzheimer's disease may eventually be tapped for a different purpose altogether: re-growing the ends of injured nerves to relieve pain and paralysis. According to a new study, experimental compounds originally designed to combat a protein that builds up in Alzheimer's-addled brains appear to make crushed or cut nerve endings grow back significantly faster, a potential boon for those who suffer from neuropathies or traumatic injuries. ... > full story

Normal breast cells help kill cancer cells, researchers find (April 14, 2011) -- Researchers have shown that normal breast cells help defend against cancer by producing the protein interleukin 25 to actively and specifically kill breast cancer cells. This important new finding points the way to a new therapeutic target for breast cancer treatment. ... > full story

New evidence that chronic ulcerative stomatitis is an autoimmune disease (April 14, 2011) -- In a study investigating the cause of a little-understood condition called chronic ulcerative stomatitis (CUS), researchers have provided evidence that an autoimmune response contributes to the painful oral disease, supporting the classification of CUS as an autoimmune disease. ... > full story

Espresso makers: Coffee in capsules contains more furan than the rest (April 14, 2011) -- Coffee made in espresso makers, above all that made from capsules, contains more furan -- a toxic, carcinogenic compound -- than that made in traditional drip coffee makers, although the levels are still within safe health limits. ... > full story

Experimental treatment for COPD in development (April 14, 2011) -- Researchers have developed a non-steroid based strategy for improving the lung's innate immune defense and decreasing inflammation that can be a problem for patients with chronic obstructive pulmonary disease (COPD). In a study, researchers targeted the Nrf2 pathway using sulforaphane, an ingredient that is present in broccoli in a precursor form, to enhance the Nrf2 pathway in the lung that mediates the uptake of bacteria. ... > full story

Increase in deaths in men with type 2 diabetes and testosterone deficiency may be prevented by testosterone replacement, study suggests (April 14, 2011) -- A new study on men with type 2 diabetes shows that those with low levels of testosterone may die sooner unless they are given testosterone replacement therapy. ... > full story

A judge's willingness to grant parole can be influenced by breaks (April 14, 2011) -- A judge's willingness to grant parole can be influenced by the time between their latest break and their current hearing. ... > full story

Possible new approach to treating deadly leukemia in babies (April 14, 2011) -- A new study points to a promising new approach to treating an aggressive and usually fatal leukemia in babies. The study involved a type of leukemia called mixed lineage leukemia, or MLL. Only 25 to 50 percent of babies diagnosed with MLL leukemia survive the disease. ... > full story

Low intensity treadmill exercise is best to improve walking in Parkinson's, study suggests (April 14, 2011) -- Researchers found that Parkinson's patients who walked on a treadmill at a comfortable speed for a longer duration (low-intensity exercise) improved their walking more than patients who walked for less time but at an increased speed and incline (high-intensity exercise). ... > full story

Comprehensive study reveals patterns in firefighter fatalities (April 14, 2011) -- Researchers found that cultural factors in the work environment that promote getting the job done as quickly as possible with whatever resources available lead to an increase in line-of-duty firefighter fatalities. ... > full story

Stillbirths: The invisible public health problem (April 14, 2011) -- Some 2.6 million third trimester stillbirths worldwide occur every year, according to the first comprehensive set of stillbirth estimates. ... > full story

Accountable care organizations have potential to curb costs and improve health care (April 14, 2011) -- If implemented successfully, accountable care organizations (ACOs) have the ability to achieve better care, better population health, and lower costs, according to a new report released by the Commonwealth Fund Commission on a High Performance Health System. An accompanying Commonwealth Fund perspective contains an analysis of how the proposed rules for the new Medicare Shared Savings Program for ACOs issued recently by the Centers for Medicare and Medicaid Services align with these recommendations. ... > full story

Vehicle pollution significantly damages the brain, mouse study suggests (April 13, 2011) -- If mice commuted, their brains might find it progressively harder to navigate the maze of Los Angeles freeways. A new study reveals that after short-term exposure to vehicle pollution, mice showed significant brain damage -- including signs associated with memory loss and Alzheimer's disease. ... > full story

Multiple sclerosis: Risk factors in children (April 13, 2011) -- A new study identifies a particular gene involved in the immune response that puts certain children at a higher risk of developing multiple sclerosis. ... > full story

Low doses of penta-brominated diphenyl ether flame retardants alter gene expression (April 13, 2011) -- Polybrominated diphenyl ethers (PBDEs) are chemicals that have been widely used as flame retardants and are persistent organic pollutants. Human health concerns have arisen based on studies with laboratory animals exposed to high levels of PBDEs, not typical of human exposures. In this study, oral ingestion of a relatively low dose of PBDE mixture DE-71 by pregnant and lactating rats was found to increase thyroid hormones in female offspring and increase gonadal osteopontin gene expression. ... > full story

HIV rate in San Francisco could be cut sharply with expanded treatment, study predicts (April 13, 2011) -- If HIV-infected adults in San Francisco began taking antiretroviral treatments as soon as they were diagnosed, the rate of new HIV infections among men who have sex with men would be cut by almost 60 percent over five years, according to a new study. ... > full story

To students, music piracy and shoplifting are worlds apart (April 13, 2011) -- College undergrads in a new study said they thought shoplifting was immoral, but also weren't motivated to follow laws governing digital music piracy. ... > full story

Bitterness induces nausea, swallowing not required (April 13, 2011) -- The mere taste of something extremely bitter -- even if you don't swallow it at all -- is enough to cause that dreaded feeling of nausea and to set your stomach churning, according to a new study. ... > full story

Short-term, high-fat diet may initiate protection during heart attack (April 13, 2011) -- A new study shows that short-term, high-fat "splurges" within one's diet could elicit cardioprotective properties during a heart attack. ... > full story

Treatment found for rare lung disease, study suggests (April 13, 2011) -- A new study has revealed a drug approved to prevent rejection in organ transplant patients helped treat a rare lung disease in women. ... > full story

Children victims of most eye injuries from aerosols (April 13, 2011) -- A new estimate of emergency room visits for eye injuries related to aerosol spray cans finds that children account for more than half the cases. Infants and toddlers are the most common age segment affected, leading researchers to emphasize prevention. ... > full story

Cultural differences are evident deep in the brain of Caucasian and Asian people (April 13, 2011) -- People in different cultures make different assumptions about the people around them, according to a new study. The researchers studied the brain waves of people with Caucasian and Asian backgrounds and found that cultural differences in how we think about other people are embedded deep in our minds. Cultural differences are evident very deep in the brain, challenging a commonsense notion that culture is skin deep. ... > full story


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